M. Sinan Gönül

Learn More
Cutaneous metastases may be either the initial manifestation of an internal malignancy or represent recurrent neoplastic disease. The aim of this study was to investigate the incidence and characteristics of cutaneous metastases in cases of internal malignancy. A total of 1287 patients with internal malignancy were included in the study. Dermatological(More)
BACKGROUND Pigmented purpuric dermatoses (PPD) are chronic, recurrent group of disorders characterized by petechial and pigmentary macules usually localized on the lower limbs. Its etiopathogenesis is unknown. There are very few clinical and etiological studies on PPD in the literature. OBJECTIVE We aim to examine the etiopathogenetic factors of PPD(More)
Lichen planus (LP) is a skin disease characterized by violaceous, polygonal, flat-topped papules and plaques. The form with lichenoid papules in linear distribution is called linear lichen planus (LLP). It is usually distributed unilaterally and follows Blaschko lines. Lichen planus is seen in less than 0.2% of all LP patients [1]. To our knowledge, there(More)
70 Papular elastorrhexis (PE) is a rare disorder of elastic tissue characterized by asymptomatic, nonfollicular, whitish or flesh-coloured, monomorphous, discrete, oval to round papules [1–5]. One to five mm-sized papules are symmetrically distributed on the chest, abdomen, back and upper limbs [1, 3, 4]. Some PE cases may be underestimated because of the(More)
The incidence of melanoma has recently been increasing. BRAF mutations have been found in 40-60% of melanomas. The increased activity of BRAF V600E leads to the activation of downstream signaling through the mitogen-activated protein kinase (MAPK) pathway, which plays a key role as a regulator of cell growth, differentiation, and survival. The use of BRAF(More)
INTRODUCTION Lichen planus (LP) is a papulosquamous eruption of the skin and mucous membranes. Although the exact pathogenesis of the disease remains unclear, it is believed that LP represents an inflammatory disorder. Neutrophil-lymphocyte (N/L) ratio is considered a systemic inflammatory marker that correlated with severity of the diseases. AIM To(More)
An 82-year-old male presented with rash, burning, and itching on his knees that had started 4 days after the local application of Mandragora Radix sap for 3 consecutive days. A dermatological examination revealed erythematous, edematous, and scaly plaque lesions on the patient's knees. An open application test with M. Radix was performed, and the patient(More)
INTRODUCTION Viral warts are common skin condition caused by the human papilloma virus. AIM To determine the clinical features of warts and therapeutic approaches to warts and compare them with the literature. MATERIAL AND METHODS A cross-sectional survey was conducted on 362 consecutive patients presenting to a dermatology clinic in Ankara, Middle(More)