M. Schroeder

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The aim of the treatment study was to interfere with the coagulative as well as the fibrinolytic properties of the tumours. To 18 women over 70 years off age, and not suitable for treatment with eytostatics, the anticoagulant Warfarin was given together with the f~brinolytie inhibitor tranexamic acid (Cyklokapron) in a dosage of 4 g daily. All patients were(More)
Current progress in the treatment of unresectable non-small-cell lung cancer (NSCLC) is reviewed. Several new agents including vinorelbine, paclitaxel, docetaxel, gemcitabine, and irinotecan have been shown to have distinct activity for NSCLC. Combinations of a new agent with cisplatin or carboplatin were highly active for advanced NSCLC, and randomized(More)
We studied the replacement of cyclophosphamide by IF in the well known VAC regimen. IF was adm|nistered 3000 mg/m2/i.v, day one and two every 4 weeks. Vincrlstine 1.5 mg/m2/i .v, push on day one, every 2 weeks. Actinomycin D 900 ~g/m2/i .v. day one and two every 4 weeks. We studied 3 groups of patients treated with thls IVA regimen. Group A: 18 patients(More)
Patients with small cell carcinoma of the lung (SCCL) were treated in two multicenter trials with different cytostatic drug regimens including ifosfamide. In the first randomized study, including 306 patients, alternating chemotherapy with VP 16, ifosfamide, vindesine (VPIV), adriamycin, cisplatinum, vincristine (APO), and cyclophosphamide, methotrexate,(More)
The efficacy of ifosfamide (6o mg/kg, d1-5) and vindesine (3 mg/m 2, d1+(5)) as second line chemotherapy was investigated in 26 male patients (pts) with small cell lung cancer (SCLC) resistant ( pts) to first line therapy or relapsing (17pts) after transient remission. Median age of the pts was 53 years, range 33-74, median perfor mance status 7o%, range(More)
In advanced HNC, combined modality treatment with chemotherapy followed by surgery and/or radiotherapy (RT) appears to be superior to chemotherapy (CT) or radiotherapy alone. In a prospective randomized study we compared the results of CT+RT (regimen A) to CT alone (regimen B) in advanced HNC. The administered drugs consisted of cis-platinum 60mg/m2(day(More)
Ue report about a retrospective study of a patient collective from the files of the Radiological Clinic of MOnster University between i.i.1960 and ]0~.1985. There were 79 cases of primary malignant tumors of the lower jaw in 50 male and 29 f e m a l e p a t i e n t s . More t h a n 60 Z of these patients ~ere 60 years and elder when treatment started. 63 of(More)
1/6, duration 28 months. After this period, in addition to local recurrence there was progress of the lung metastases. In three pts the primary tumor was subtotally resected. These patients presented no measurable tumor parameter and so far after i0 months observation there is no evidence of recurrence. Conclusions: Preliminary results of this combination(More)
MP VERSUS VCMP: A PROSPECTIVE RANDOMIZED TRIAL IN STAGE I I AND I I I MULTIPLE MYELOMA. D.Peest, H.J.Schmoll, l . Schedel, H.Deicher, l . B o l l , U.Essers, H.Gamm, S.Gl~ck, K.GBrg, M.Grematzki, Chr.Hauswaldt, E.Heilmann, V.Hiemeyer, J.Karow, U.Kindler, A.Osrte l , M.Pfreundschuh, M.Planker, H.M.Reinold, E.Sch~fer, K.Schumaeher, B.Stenger, B.R.Suehy,(More)