M Schawaller

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The subunit composition of env glycoproteins isolated from HIV-infected cell membranes, virus particles, and baculovirus recombinant-infected insect cells has been investigated using a number of crosslinking reagents. The results obtained provide evidence that gp160 is a tetramer of identical subunits and that gp41 is also tetrameric.
Severe neonatal alloimmune thrombocytopenia and patients with HPA-1a-specific antibodies require transfusion of HPA-1a-negative platelets. Identifying HPA-1a-negative donors requires simple and reliable typing methods. Most existing techniques use polyclonal antibodies, are time consuming and involve platelet isolation. We have used a horseradish peroxidase(More)
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