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Interactions of platinum complexes, peptides, methionine and dehydrogenases.
- P. Melius, C. A. Mcauliffe, I. Photaki, M. Sakarellou-Daitsiotou
- Chemistry, Medicine
- Bioinorganic chemistry
Eight platinum-methionine complexes have been investigated as inhibitors of the alcohol (EC 22.214.171.124) and lactate (EC 126.96.36.199) dehydrogenase systems. While only one complex, Pt(Met)Cl2, had two… Expand
Synthesis and catalytic properties of peptides containing amino-acids involved in the active centres of hydrolytic enzymes.
Seven oligopeptides of the type indicated in the title have been synthesised and found to catalyse the hydrolysis of p-nitrophenyl acetate with a catalytic activity of ca. 30–50% of that of imidazole.