M. S. Sridhar

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PURPOSE To identify current indications and trends in indications for penetrating keratoplasty and associated procedures. METHODS Retrospective chart review of all patients who underwent penetrating keratoplasty at Wills Eye Hospital from January 1, 1996 to December 31, 2000. RESULTS A total of 1,529 corneal transplants were performed during this 5-year(More)
OBJECTIVE To report the clinical features and outcome of patients with pellucid marginal corneal degeneration (PMCD). DESIGN Retrospective noncomparative case series. METHODS Retrospective chart review of 116 eyes of 58 patients with PMCD seen between 1990 and 2002 at the Cornea Service at L.V. Prasad Eye Institute, Hyderabad, India. The diagnosis of(More)
PURPOSE To present the clinical profile, laboratory results, and outcome of treatment in 16 patients with Nocardia keratitis. METHODS A retrospective review of 16 culture-proven cases of Nocardia keratitis was done. Clinical and microbiologic data were analyzed. RESULTS Nocardia constituted 1.7% of laboratory-confirmed bacterial keratitis and was seen(More)
Nocardia are aerobic, gram-positive, nonmotile and branching filamentous bacteria. Corneal infection by Nocardia is rare. Trauma is the most common predisposing factor. Isolated case reports of nocardial infection associated with contact lens wear and laser in situ keratomileusis (LASIK) have been reported. The clinical picture usually consists of(More)
PURPOSE To report our experience with amniotic membrane transplantation in the management of severe shield ulcers. DESIGN Retrospective, interventional, noncomparative case series. PARTICIPANTS Four patients (seven eyes) with grade 2 (ulcer with opaque base) and grade 3 (plaquelike lesions) shield ulcers not responding to steroid therapy with or without(More)
PURPOSE To compare the efficacy of phototherapeutic keratectomy (PTK) to epithelial debridement and polishing of Bowman's membrane using a diamond burr (DB) in the treatment of recurrent corneal erosions associated with anterior basement membrane (ABM) dystrophy. DESIGN Retrospective nonrandomized comparative trial. METHODS Medical records of 39(More)
Laser-in-situ-keratomileusis (LASIK) has become a popular technique of refractive surgery because of lower postoperative discomfort, early visual rehabilitation and decreased postoperative haze. Compared to photorefractive keratectomy (PRK), LASIK involves an additional procedure of creating a corneal flap. This may result in complications related to the(More)
PURPOSE To present a case of chemical injury and a case of thermal injury treated by amniotic membrane transplantation in acute phase. METHODS Case reports. An eye with sodium hydroxide injury, opaque cornea, and limbal ischemia of more than 180 degrees and an eye with hot tea injury, opaque cornea, stromal edema, and scarring were treated by amniotic(More)
Allelic heterogeneity of the carbohydrate sulfotransferase-6 gene in patients with macular corneal dystrophy. Macular corneal dystrophy (MCD) is an autosomal recessive disorder characterized by grayish white opacities in the cornea. It is caused by mutations in the carbohydrate sulfotransferase-6 (CHST6) gene, which codes for the enzyme corneal(More)