M. S. Prasada Babu

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REVIEW REVIEW The common view is that functional proteins or protein domains have unique and stable 3D structures characterized by the relatively fixed positions of their atoms and backbone Ramachandran angles that both vary slightly around their equilibrium positions due to low-amplitude thermal fluctuations. In addition there is another class of(More)
Evolution of eukaryotic genome architecture: Insights from the study of a rapidly evolving metazoan, Oikopleura dioica Non-adaptive forces such as elevated mutation rates may influence the evolution of genome architecture Recent sequencing of the metazoan Oikopleura dioica genome has provided important insights, which challenges the current understanding of(More)
— ERP systems contain huge amounts of data related to the actual execution of business processes. These systems have a particular way of recording activities which results in an unclear display of business processes in event logs. Several works have been conducted on ERP systems, most of them focusing on the development of new algorithms for the automatic(More)
In the title mol-ecule, C(20)H(18)BrFN(2)O(2)S, the pyrimidine ring adopts a flattened envelope conformation. The halogenated benzene ring is orthogonal to the planar part of the pyrimidine ring [dihedral angle = 89.05 (4)°], while the other phenyl ring is oriented at an angle of 85.14 (5)°. The ethoxy group is disordered over two orientations with site(More)
The title compound, C(16)H(11)BrN(2)O(2)·H(2)O, exists in a trans conformation with respect to the N=C bond [1.2815 (14) Å] and the benzofuran ring system forms a dihedral angle of 2.96 (5)° with the benzene ring. In the crystal, the ketone O atom accepts two O-H⋯O and one C-H⋯O hydrogen bond, and the water O atom accepts an N-H⋯O inter-action. Together,(More)
In the title compound, C(16)H(14)F(6)N(2)O(3), the dihydro-pyrimid-in-one ring adopts an envelope conformation. In the crystal, mol-ecules are linked by N-H⋯O and C-H⋯O hydrogen bonds into a ribbon-like structure along the b axis. In the ribbon, a pair of bifurcated acceptor N-H⋯O and C-H⋯O bonds generate an R(2) (1)(6) ring motif. Adjacent ribbons are(More)
The title compound, C(16)H(11)ClN(2)O(2)·H(2)O, exists in an E conformation with respect to the N=C bond. The benzofuran ring system forms a dihedral angle of 1.26 (4)° with the benzene ring. In the crystal, mol-ecules are linked via (N,C)-H⋯O bifurcated acceptor hydrogen bonds and (O,O,C)-H⋯O trifurcated acceptor hydrogen bonds, forming layers parallel to(More)
This chapter aims to provide an introduction to the analysis of gene expression data obtained using microarray experiments. It has been divided into four sections. The fi rst section provides basic concepts on the working of microarrays and describes the basic principles behind a microarray experiment. The second section deals with the representation and(More)
Clustering is an important data mining technique where we will be interested in maximizing intracluster distance and also minimizing intercluster distance. We have utilized clustering techniques for detecting deviation in product sales and also to identify and compare sales over a particular period of time. Clustering is suited to group items that seem to(More)
The asymmetric unit of the title compound, C(20)H(18)F(2)N(2)O(2)S, contains four independent mol-ecules, two of which are paired into a dimer by way of two N-H⋯S hydrogen bonds. The other two independent mol-ecules are paired into two centrosymmetric dimers via pairs of inter-molecular N-H⋯S hydrogen bonds. In one mol-ecule, the carboxyl-ate O atoms,(More)