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GF120918, at 250 ng/ml, increased the sensitivity of a P-glycoprotein (P-gp)-mediated multidrug resistant (MDR) small cell lung cancer cell line (H69/LX4) to the P-gp substrates, paclitaxel,Continue Reading
  • Enid G. Shephard, Ronald Anderson, +4 authors Frederick C. de Beer
  • Biology, Medicine
  • Journal of immunology
  • 1990 (First Publication: 1 September 1990)
  • We have recently provided evidence that C-reactive protein (CRP) could act as an up-regulatable substrate for membrane-associated neutrophil serine protease(s). The resultant degradation of CRPContinue Reading
  • M S Myer
  • Biology, Medicine
  • The Onderstepoort journal of veterinary research
  • 1982 (First Publication: 1 June 1982)
  • INTRODUCflON Paneth cells, normally occurring as a small group or as isolated cells in the deepest part of the duodenal crypts of Lieberkiihn, have traditionally been described as absent in theContinue Reading
  • Constance Elizabeth Jansen van Rensburg, Ronald Anderson, Gisela Käthe Jooné, M S Myer, John O'Sullivan
  • Medicine
  • Anti-cancer drugs
  • 1997 (First Publication: 1 August 1997)
  • The multidrug resistance (MDR)-neutralizing and cytotoxic properties of 16 novel tetramethylpiperidine (TMP)-substituted phenazines were compared with those of clofazimine and B669 using aContinue Reading
  • Constance Elizabeth Jansen van Rensburg, Ronald Anderson, M S Myer, Gisela Käthe Jooné, John O'Sullivan
  • Biology, Medicine
  • Cancer letters
  • 1994 (First Publication: 1 September 1994)
  • The potential of the riminophenazine agents clofazimine and B669, at therapeutically relevant concentrations, to reverse P-glycoprotein-mediated multidrug-resistance (MDR) in a human lung cancer cellContinue Reading
  • M S Myer, Daniel Wynand Verwoerd, Helen M. Garnett
  • Biology, Medicine
  • The Onderstepoort journal of veterinary research
  • 1987
  • Both growth-inhibitory and growth-stimulatory factors were detected in vitro in medium from chemotactically stimulated cultures of lung lavage cells. The macrophage component of the lavage cells wasContinue Reading
  • Ronald Anderson, Constance Elizabeth Jansen van Rensburg, M S Myer
  • Medicine
  • Toxicology and applied pharmacology
  • 1994
  • At concentrations of 0.5 microM and upward, cyclosporin A (CsA) caused dose-related inhibition of the growth of a hamster renal tubular cell line (HAK ATCC; CCL15) in vitro. Inhibition of cell growthContinue Reading