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A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis
To investigate the in vivo metabolic effects of treatment with BPR0912, a novel and potent peripheral cannabinoid receptor 1 (CB1R) antagonist, on both normal mice and diet‐induced obese (DIO) mice.
Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors
- R. S. Vijayakumar, Y. Lin, +6 authors M. Hung
- Chemistry, Medicine
- International Journal of Obesity
- 1 July 2012
Objective:Fatty acid oxidation has been implicated in amelioration of obesity by burning off excessive accumulated lipid. BPR697, a peripheral cannabinoid receptor 1 (CB1) antagonist, elevated fat… Expand
Automatic Tracking and Manipulation for Cell Lysis System Development
An automatic platform for cell localization using image processing and electroosmotic flow technology was developed and used the in vivo human leukemic cells (U937) experiments. The in vivo cells… Expand