M S Holzhäuer-Oitzl

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The conditioned place preference paradigm was used to assess the reinforcing properties of substance P, injected unilaterally into the region of the nucleus basalis magnocellularis of rats. Over three baseline trials the rats spent more time in either the black (in most cases) or white compartment of the test box (i.e. preferred one compartment). On Day 4(More)
Reinforcing properties of substance P (SP) were investigated in rats using a conditioned place preference paradigm. After three baseline trials one conditioning trial of 10 min duration was performed. Either SP (100 pg, 1 ng, 100 ng) or saline (SI) was injected unilaterally into the lateral hypothalamus or a sham injection (OC) was given. Pairing one(More)
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