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As modern data mining applications increase in complexity, so too do their demands for resources. Grid computing is one of several emerging networked computing paradigms promising to meet the requirements of heterogeneous, large-scale, and distributed data mining applications. Despite this promise, there are still too many issues to be resolved before grid(More)
Expansion of CAG repeats, which code for the disease-causing polyglutamine protein, is a common feature in polyglutamine diseases. RNA-mediated mechanisms that contribute to neuropathology in polyglutamine diseases are important. RNA-toxicity describes a phenomenon by which the mutant CAG repeat RNA recruits RNA-binding proteins, thereby leading to aberrant(More)
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