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Cyclosporine has been described to increase the sympathetic tone. Alterations in sympathetic tone may contribute to baroreceptor dysfunction. Therefore, in this study baroreceptor function in 20 kidney transplant recipients was investigated under both low and high cyclosporine whole blood concentrations using the sequence analysis technique. The sympathetic(More)
Kidney transplant recipients as well as patients on hemodialysis frequently share an increased risk of cardiovascular diseases. Besides other factors, modulations in central neural blood pressure regulation have to be considered as a pathogenetic factor. In this study, baroreceptor function as a possible modulator of blood pressure and the activity of the(More)
1. Disturbances of the blood pressure regulation, probably due to dysfunction of the autonomic nervous system, are well known complications in chronic renal failure. Haemodialysis and transplantation have been reported to ameliorate nerve dysfunction. 2. In this study, the function of the blood pressure control was investigated in kidney transplant(More)
OBJECTIVE To investigate progression of peripheral and central sensory tract lesion and its correlation to immunological deterioration. METHODS Clinical and neurophysiological investigation (evoked potentials of the median and tibial nerve) and immunological parameters (CD4-cells, beta 2-microglobuline) were followed up in 160 patients (24 females, 136(More)
Recent studies showed that to smoke four cigarettes within one hour impairs baroreflex sensitivity in humans. In the present study, these effects were qualified more precisely from blood pressure and heart rate records by a sequence analysis and by Fourier analysis of Finapres-registrations. The Mayer waves of the heart rate PDS (power density spectrum),(More)
In addition to opportunistic infections, neoplasms or cerebrovascular complications, metabolic encephalopathies are a classical cause of diffuse brain dysfunction in HIV infection and are frequent in the terminal stage. We report an HIV-infected patient with symmetrical, focally increased signal in the midbrain on proton density- and T1-weighted MRI without(More)
A 37-year-old man with hemophilia B, acquired immunodeficiency syndrome, and a unilateral cytomegalovirus retinitis developed a central retinal vein occlusion. This vascular complication occurred despite effective antiviral drug treatment with improvement of the fundus and despite decreased blood coagulability due to hemophilia B. Additional analyses of(More)
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