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Duchenne muscular dystrophy (DMD) is one of the most frequent forms of muscular disorders. It is caused by the absence of dystrophin, a core component of the sarcolemma-associated junctional complex that links the cytoskeleton to the extracellular matrix. We showed previously that plectin 1f (P1f), one of the major muscle-expressed isoforms of the(More)
Mutations in the cytolinker protein plectin lead to grossly distorted morphology of neuromuscular junctions (NMJs) in patients suffering from epidermolysis bullosa simplex (EBS)-muscular dystrophy (MS) with myasthenic syndrome (MyS). Here we investigated whether plectin contributes to the structural integrity of NMJs by linking them to the postsynaptic(More)
Lipid transfer protein (LTP) is a major allergen in peach often causing anaphylactic reactions with a high prevalence of sensitization in the Mediterranean area. The prevalence of LTP sensitization in Central Europe is currently unknown, where the diagnosis is complicated by a high background sensitization to the major birch pollen allergen, Bet v 1, and(More)
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