M. R. Lucreziotti

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Propionyl-L-carnitine (PLC) has been shown to exert beneficial effects in experimental models of peripheral arterial diseases, such as ergotamine-induced tail gangrene and bilateral femoral arteries occlusion in rats. These models, however, present some drawbacks. The present study was performed to determine whether repeated oral administration of PLC(More)
The effects of long-term treatment (11 months) with acetyl-L-carnitine (75 mg/kg daily) on the morphology of brain and optic nerve was studied in 16 senescent (22-month-old) Wistar rats (nine untreated, seven treated). Five young rats (aged 3 months) were used for comparison. Senescence was found to cause a structural disorganization of cerebral cortex,(More)
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