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- Publications
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Folic acid and trastuzumab conjugated redox responsive random multiblock copolymeric nanocarriers for breast cancer therapy: In-vitro and in-vivo studies.
- Arun Kumar, Shantanu V. Lale, M. R. Aji Alex, V. Choudhary, V. Koul
- Chemistry, Medicine
- Colloids and surfaces. B, Biointerfaces
- 2017
The study represents synthesis, characterization and biological evaluation of redox responsive polymeric nanoparticles based on random multiblock copolymer for doxorubicin delivery in breast cancer.… Expand
Self assembled dual responsive micelles stabilized with protein for co-delivery of drug and siRNA in cancer therapy.
- M. R. Aji Alex, Chetan Nehate, S. Veeranarayanan, D. S. Kumar, R. Kulshreshtha, V. Koul
- Materials Science, Medicine
- Biomaterials
- 1 July 2017
Design of safe and efficient vehicles for the combinatorial delivery of drugs and genetic agents is an emerging requisite for achieving enhanced therapeutic effect in cancer. Even though several… Expand
Combinatorial delivery of superparamagnetic iron oxide nanoparticles (γFe2O3) and doxorubicin using folate conjugated redox sensitive multiblock polymeric nanocarriers for enhancing the…
- Chetan Nehate, M. R. Aji Alex, A. Kumar, V. Koul
- Materials Science, Medicine
- Materials science & engineering. C, Materials for…
- 1 June 2017
Redox sensitive, folate conjugated multiblock polymeric system of (-PLGA-PEG-PLGA-urethane-ss-) demonstrated self-assembly into stable nanoplatforms. The polymeric nanocarriers were encapsulated with… Expand
Eugenol nanocapsule for enhanced therapeutic activity against periodontal infections
- K. Pramod, M. R. Aji Alex, Manisha Singh, S. Dang, S. Ansari, J. Ali
- Chemistry, Medicine
- Journal of drug targeting
- 2 January 2016
Abstract Eugenol is a godsend to dental care due to its analgesic, local anesthetic, and anti-inflammatory and antibacterial effects. The aim of the present research work was to prepare, characterize… Expand
Click modified amphiphilic graft copolymeric micelles of poly(styrene-alt-maleic anhydride) for combinatorial delivery of doxorubicin and plk-1 siRNA in cancer therapy.
- M. R. Aji Alex, S. Veeranarayanan, A. C. Poulose, Chetan Nehate, D. S. Kumar, V. Koul
- Materials Science, Medicine
- Journal of materials chemistry. B
- 16 November 2016
The anti-apoptotic defense mechanism of cancer cells poses a major hurdle which makes chemotherapy less effective. Combinatorial delivery of drugs and siRNAs targeting anti-apoptotic proteins is a… Expand