M Paz Viveros

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To investigate the physiological role of the delta-opioid receptor during the preweanling period, we have studied the effects of chronic (daily injections from birth to postnatal day 19) and acute treatments with the selective delta-antagonist naltrindole (1 mg/kg), on behavioural and nociceptive responses in 20-day old male rats. Behavioural testing was(More)
The effects of a daily injection of the opioid antagonist naltrexone (NALTX, 1 mg/kg SC), from birth to weaning day, on several behavioral parameters were investigated in adult rats of both genders. This work uses three behavioral tests. The use of the open-field test in addition to the holeboard and plus-maze tests allows the measurement of complementary(More)
To address the existence of possible functional interactions between delta- and mu- receptors in relation to the affective component of pain, we have studied the effects of functional blockade of delta-receptors by a chronic treatment with naltrindole (1 mg/kg, 8 consecutive days) on antinociceptive responses to morphine (2 and 5 mg/kg) in the tail electric(More)
The effects of a daily injection of the opioid antagonist naltrexone (NALTX, 1 mg/kg, s.c.) from birth to weaning on various parameters were investigated in male and female rats during postnatal development until adulthood. NALTX increased cerebellar DNA and protein content as well as cerebellar weight at 7 days. Eye opening was not affected by NALTX but it(More)
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