M. Pavana Ravi Sai Kiran

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Optimal levels of ftsZ gene product are shown to be required for initiation of the cell division process in Mycobacterium tuberculosis. Here, we report that the ftsZ gene expression is sharply down-regulated during starvation and hypoxia, conditions that are believed to result in growth arrest, but is restored upon dilution of cultures into fresh(More)
Bacterial cell division and cell wall synthesis are highly coordinated processes involving multiple proteins. Here, we show that Rv0008c, a novel small membrane protein from Mycobacterium tuberculosis, localizes to the poles and on membranes and shows an overall punctate localization throughout the cell. Furthermore, Rv0008c interacts with two proteins,(More)
The role(s) in cell division of the Mycobacterium tuberculosis Rv0011c gene product, a homolog of the Streptomyces CrgA protein that is responsible for coordinating growth and cytokinesis in sporogenic aerial hyphae, is largely unknown. We show that an enhanced cyan fluorescent protein-M. tuberculosis CrgA (ECFP-CrgA(MT)) fusion protein is localized to the(More)
In the remote health care monitoring applications, the collected medical data from bio-medical sensors should be transmitted to the nearest gateway for further processing. Transmission of data contributes to a significant amount of power consumption by the transmitter and increase in the network traffic. In this paper we propose a low complex rule engine(More)
FtsZ assembly at the midcell division site in the form of a Z-ring is crucial for initiation of the cell division process in eubacteria. It is largely unknown how this process is regulated in the human pathogen Mycobacterium tuberculosis. Here we show that the expression of clpX was upregulated upon macrophage infection and exposure to cephalexin(More)
FtsH is an essential membrane-bound protease that degrades integral membrane proteins as well as cytoplasmic proteins. We show that Mycobacterium tuberculosis (Mtb) ftsH expression levels are upregulated upon exposure to agents that produce reactive oxygen and nitrogen intermediates (ROI and RNI) and growth in macrophages. In partial support of this result(More)
Studies on IEEE 802.15.4 MAC in the current literature for anycast multi-hop networks do not capture a node’s behaviour accurately. Due to the inaccurate modeling of state-wise behaviour of a node, the optimization of network parameters has not been efficient so far. In this work, we include the state-wise behaviour of a relay node into a 3D Markov model to(More)
In this paper, we propose and model an enhanced IEEE 802.15.4 MAC for sensor nodes operating in multi-hop scenarios. Existing IEEE 802.15.4 MAC, when adapted to multi-hop networks may not perform efficiently due to lack of knowledge about the instantaneous state of local gateway. We therefore ameliorate the channel access mechanism by introducing a new(More)
In this study, we propose a novel physical layer architecture which is a hybrid of IEEE 802.15.4 and IEEE 802.11b for providing ubiquitous connectivity in IoT remote sensing platforms. The proposed architecture multiplexes the commonly available functional units of IEEE 802.15.4 and IEEE 802.11b, thereby achieving significant area and power savings. In(More)
Abstract—Technological development in the area of wireless communications lead to the requirement of tight integration of both the digital and analog functional units. Integrating mixers is a challenging task, especially in mixed signal design. IoT communication devices require low design complexity as we expect millions of devices connected. In this paper(More)
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