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beta-Amyloid peptides are neurotoxic when applied to primary cultures of hippocampal neurones from the embryonic rat. This neurotoxic effect can be inhibited completely by certain disazo dyestuffs. The most potent of these are Congo Red and Congo Rubin, whilst Direct Garnet and sodium 4-aminonaphthalene-1-sulphonate are inactive. Congo Red also inhibits the(More)
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