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Service-oriented systems are becoming more and more nodes in a digital, dynamic ecosystem requiring the identification and establishment of flexible, spontaneous collaboration activities between services. This requires new engineering approaches that can integrate new functionalities and behaviours into existing running systems of active, distributed and(More)
There is a large body of research on software services, but the issues of communication and dynamic reconfiguration have received little attention, as have adaptation to environment and dynamic combination of service building blocks into new applications. Here, we present the approach of the FP7 ALIVE project to the use of formal models of coordination and(More)
As a methodology for characterizing substances with regard to its viability in direct compression, the SeDeM Diagram Expert System may be considered a new tool in terms of the number of parameters applied and its optimization. The paper is based on the experimental SeDeM characterization study of 51 directly compressible (DC) excipients. After selecting the(More)
The new SeDeM Method is proposed for testing the batch-to-batch reproducibility of the same active pharmaceutical ingredient (API) in powder form. The procedure describes the study of the galenic properties of substances in powder form in terms of the applicability of direct compression technology. Through experimental determination of the SeDeM Method(More)
As a methodology for characterizing substances in relation to their viability in direct compression, the SeDeM Diagram Expert System may be considered an open system in terms of the number of parameters applied and the optimization of these parameters. With the experience acquired from applying the SeDeM Diagram, in this study, we propose optimizing the(More)
Application of the new SeDeM Method is proposed for the study of the galenic properties of excipients in terms of the applicability of direct-compression technology. Through experimental studies of the parameters of the SeDeM Method and their subsequent mathematical treatment and graphical expression (SeDeM Diagram), six different DC diluents were analysed(More)
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