M. P. V. V. B. Singh

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Cancer chemoprevention by natural dietary agents has received considerable importance because of their cost-effectiveness and wide safety margin. However, single agent intervention has failed to bring the expected outcome in clinical trials; therefore, combinations of chemopreventive agents are gaining increasing popularity. The present study aims to(More)
In spite of proficient results of several phytochemicals in preclinical settings, the conversion rate from bench to bedside is not very encouraging. Many reasons are attributed to this limited success, including inefficient systemic delivery and bioavailability under in vivo conditions. To achieve improved efficacy, polyphenolic constituents of black(More)
Skin cancer is still a major cause of morbidity and mortality worldwide. Skin overexposure to ultraviolet irradiations, chemicals, and several viruses has a capability to cause severe skin-related disorders including immunosuppression and skin cancer. These factors act in sequence at various steps of skin carcinogenesis via initiation, promotion, and/or(More)
Glyphosate (N-(phosphonomethyl) glycine, C(3)H(8)NO(5)P), a herbicide, used to control unwanted annual and perennial plants all over the world. Nevertheless, occupational and environmental exposure to pesticides can pose a threat to nontarget species including human beings. Therefore, in the present study, genotoxic effects of the herbicide glyphosate were(More)
The clinical success of the applicability of tea polyphenols awaits efficient systemic delivery and bioavailability. Herein, following the concept of nanochemoprevention, which uses nanotechnology for enhancing the efficacy of chemotherapeutic drugs, we employed tea polyphenols, namely theaflavin (TF) and epigallocatechin-3-gallate (EGCG) encapsulated in a(More)
Seed priming is a crucial method to induce tolerance capabilities in plants against various abiotic stresses. Seed priming is associated with an induction of number of physiological and biochemical changes in plants by the treatment of natural and/or synthetic compounds to the seeds before their germination. The aim of this study was to investigate whether(More)
Modern agriculture is facing significant challenges due to the high complexity of field conditions caused not only by currently ongoing global climatic change but also by stress combinations. Recent research is focusing on the molecular mechanisms controlling stress responses in plants. Many efforts have been made to uncover the complex but well-coordinated(More)
The aim of the present study was to investigate the effect of photoinhibitory light induced changes under cadmium stress in electron transport activity, active oxygen species (AOS) generation, oxidative damage, photorespiration, enzymatic and non-enzymatic (low molecular weight) antioxidants in cyanobacterium, Aphanothece stagnina. The photosynthetic(More)
In the present investigation Jatropha and pea plant leafs was used, to germinated the plant by artificial condition through plant tissue culture method. We have taken three methods Method A, B & C to germinate callus, seed, bud and stem. 30 Sample were taken to analyze. In Method A 60% samples were contaminated (fungus and bacteria) and 20% was shown(More)
We acknowledge the following for their help with this study. The contents of this study reflect the views of the authors, who are responsible for the facts and the accuracy of the information provided herein. This document is disseminated under the sponsorship of the US Department of Transportation's University Transportation Centers Program and the Iowa(More)
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