M P Fichman
Highly Influential Citations8
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ABSTRACT The effect of antidiuretic hormone (ADH) and water retention on plasma renin (PRA) and aldosterone was studied in 4 cases of SIADH with serum sodium concentration less than 120 mEq/l and in… Continue Reading
IN normal man osmolality, or concentration of osmotically active solutes in body fluids or total body water, is remarkably constant despite large variations in water and solute intake and excretion...
A patient with unilateral ureteral obstruction at the ureteropelvic junction had hypertension of one year's duration. Increased activity of the renin-angiotensin system was documented by means of… Continue Reading
Increased renal prostaglandins activated by beta-catecholamines could produce renal tubular sodium wasting and angiotensin pressor resistance observed in Bartter's syndrome. We therefore measured… Continue Reading
INCREASED secretion of antidiuretic hormone (ADH) has been implicated in many hyponatremic disorders associated with impaired water excretion. This increased ADH release may be due to nonosmotic… Continue Reading
Urinary cyclic AMP (UcAMP) appropriate for the serum calcium concentration was determined in normal subjects during the base-line state and during alteration in their serum calcium concentrations by… Continue Reading
Abstract Enhanced prostaglandin production, possibly stimulated by hypokalemia, may mediate the manifestations of Bartter's syndrome. To investigate the cause of increased urinary prostaglandin… Continue Reading
ABSTRACT Vasopressin (ADH) (10 mU/min) was infused for 2–4 hr in 6 water loaded normal subjects, 5 patients with primary diabetes insipidus, and 2 with nephrogenic diabetes insipidus. Cyclic AMP in… Continue Reading