Learn More
In this report we document the results of several independent studies testing the sensitivity, specificity and reliability of the Prionics Western blotting (PWB) procedure to detect bovine and ovine disease-specific, protease-resistant prion protein (PrPSc). Validation of the technique was obtained by blind analysis of samples from cattle affected with(More)
Before specific therapy, such as oral corticosteroids, can be commenced it is essential to distinguish full-blown allergic bronchopulmonary aspergillosis (ABPA) from allergy to A. fumigatus in patients with cystic fibrosis (CF). For this purpose we have evaluated the diagnostic value of recombinant A. fumigatus allergen I/a (rAsp f I/a)-specific serology in(More)
  • M. Moser
  • 2005
Im Rahmen unserer Untersuchungen tiber die praktische Anwendung der Ergebnisse der Mykorrhizaforschung bei Aufforstungen in Gebirgslagen (MosER 1956) ergaben sich f~ir uns zwei haupts~ichliche Arbeitsrichtungen: 1. die kiinstliche Impfung yon Forstpflanzen mit Mykorrhizapilzen und 2. die Aktivierung allenfalls im Boden vorhandener aber ol°c inaktiver(More)
Aspergillus fumigatus secretes an 18-kDa nonglycosylated IgE-binding protein. This protein was previously shown to be a ribotoxin, like alpha-sarcin and mitogillin. A 686-bp long A. fumigatus cDNA encoding an 18-kDa ribotoxin was cloned and expressed in Escherichia coli as a fusion protein with six adjacent histidines (rAsp f I/a). rAsp f I/a was purified(More)
A 32-kDa nonglycosylated alkaline protease (EC 3.4.1.14) with elastolytic activity, secreted by the opportunistic pathogen Aspergillus fumigatus ATCC 42202, is suggested to be a virulence factor of this fungus. The enzyme is a serine protease of the subtilisin family, and its cDNA nucleotide sequence has recently been reported. We have cloned the cDNA(More)
BACKGROUND We report a clinical study comparing the recombinant Aspergillus fumigatus allergen I/a (rAsp f I/a) to two commercial A. fumigatus extracts in skin prick tests, intradermal tests, and serologic assays. METHODS Patients with allergic bronchopulmonary aspergillosis and A. fumigatus-allergic patients with asthma, and control subjects, including(More)
BACKGROUND Type I allergy represents a severe health problem in industrialized countries where up to 20% of the population suffer from allergic rhinitis, conjunctivitis and allergic asthma bronchiale and in severe cases from anaphylaxis, leading to death. OBJECTIVE The aim of this study was to evaluate recombinant Bet v I, the major birch pollen allergen(More)
  • M. Moser
  • 2005
Abb. 4. H6henentwicklung an Kiefer und Fichte von 1940 bis 1955 /J4essung 1@4'0 zwischen 1940 und 1955 die F/Srderung des H/Shenwachstums in F1. 5 abgeklungen, obwohl die friihere Mehrleistung ihr auch heute noch den oben berechneten Vorrang sichert. Wann dieser Wendepunkt eingetreten ist, kann mangels Aufnahmen w~ihrend der bekannten Zeitspanne nicht(More)
Die Wuchsstoffbeziehungen yon Mycorrhizapilzen zur Pflanzenwurzel einerseits und zur l~hizosph&re und ihren Mikroorg~nismen andererseits, erfahren durch verschiedene Forschungsergebnisse der letzten Jahre Erg/~nzungen, die geeignet erscheinen, manche Fragen der Mycorrhizaforschung aueh yon neuen Gesichtspnn.kten ~us zu beleuchten, soweit dies ectotrophe(More)