M. Morgan

Learn More
OBJECTIVES Whole-genome sequencing potentially represents a single, rapid and cost-effective approach to defining resistance mechanisms and predicting phenotype, and strain type, for both clinical and epidemiological purposes. This retrospective study aimed to determine the efficacy of whole genome-based antimicrobial resistance prediction in clinical(More)
Whole-genome sequencing (WGS) could potentially provide a single platform for extracting all the information required to predict an organism's phenotype. However, its ability to provide accurate predictions has not yet been demonstrated in large independent studies of specific organisms. In this study, we aimed to develop a genotypic prediction method for(More)
The ability to elicit requirements in the design of new technology has proven to be particularly problematic with older generations of users who have not grown up with the same level of familiarity and understanding of present day user interfaces as younger generations have. It is also widely acknowledged that older people are poorly represented in the(More)
BACKGROUND Rare disease patients and caregivers face uncommon, serious, debilitating conditions often characterised by poor prognosis and limited treatment options. This study aimed to explore what they consider of value when choosing between hypothetical therapeutic options and to quantify both their benefit-risk preferences and the influence of disease(More)
BACKGROUND With increasingly intensive treatments and population ageing, more people face complex treatment and care decisions. We explored patterns of the decision-making processes during critical care, and sources of conflict and resolution. METHODS Ethnographic study in two Intensive Care Units (ICUs) in an inner city hospital comprising:(More)
— Cryogenic cooling of receivers to reduce their noise temperature is especially important in radio astronomy, as the antenna noise temperature is determined by the cosmic microwave background radiation (2.725 K) modified by the presence of atmosphere. For frequencies up to 120 GHz direct amplification at cryogenic temperatures is typically employed using(More)
  • 1