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BACKGROUND Brachycephalic dogs (BD) are prone to congenital upper airway obstruction (brachycephalic syndrome, BS). In humans suffering from sleep apnea, upper airway obstruction is known to cause hypertension. There is no information regarding the influence of BS in dogs on cardiorespiratory physiology. HYPOTHESIS BD are prone to lower P(a) O(2), higher(More)
BACKGROUND Pericardial effusion cytology is believed by many to be of limited value, yet few studies have evaluated its diagnostic utility. OBJECTIVES To determine the diagnostic utility of cytologic analysis of pericardial effusion in dogs and to determine if consideration of additional data could improve the diagnostic yield. ANIMALS Two hundred and(More)
  • M Mellema
  • The Veterinary clinics of North America. Small…
  • 2001
The primary goal of the intensive care clinician can be said to be to optimize global DO2. This approach is the primary means by which the greatest killers of the critically ill patient (sepsis, SIRS, multiple organ dysfunction syndrome) may be addressed at present. Optimizing DO2 means delivering just enough to meet the patient's needs, because therapeutic(More)
BACKGROUND Brachycephalic dogs are at risk for arterial hypertension and obstructive sleep apnea, which are both associated with chronic magnesium (Mg) depletion. HYPOTHESIS/OBJECTIVES To compare the period prevalence of hypomagnesemia between Boxers and Bulldogs presented to a referral teaching hospital. To screen a group of Bulldogs for evidence of(More)
OBJECTIVES To determine if bulldogs develop a hypercoagulable state comparable to that observed in human patients with sleep apnoea hypopnoea syndrome. MATERIALS AND METHODS Thromboelastography was performed in 15 clinically healthy bulldogs and 24 healthy control dogs of other breeds or mixed breed lineage. RESULTS Bulldogs had significantly shorter R(More)
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