M. Makropoulou

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BACKGROUND/PURPOSE Laser-induced autofluorescence spectroscopy provides excellent possibilities for medical diagnostics of different tissue pathologies including cancer. However, to create the whole picture of pathological changes, investigators collect spectral information from patients in vivo or they study different tumor models to obtain objective(More)
Twenty-one teeth with one root canal were prepared by the step-back technique, divided into three groups, and split longitudinally. Group A served as a control. In group B, 20 to 150 pulses of 100 micros, 30 to 70 mJ per pulse at 1 to 4 Hz from a free-running Er:YAG laser were applied to the root-canal dentin. In group C, the Q-switched Er:YAG laser, with(More)
BACKGROUND AND OBJECTIVE An effort has been made to distinguish the composition of carotid atherosclerotic plaques (CAP) from patients undergoing carotid endarterectomy, by laser induced fluorescence spectroscopy. STUDY DESIGN/MATERIALS AND METHODS Different excitation wavelengths were used: 476, 488, and 458 nm of a continuous wave krypton/argon ion(More)
. The interaction of picosecond laser radiation with human dental tissue was investigated in this study, in order to determine the ablation rates and the surface characteristics of the dentine by using scanning electron microscopy (SEM). Dentine ablation was performed by using tooth sections of different thicknesses (0.5–2.0 mm). Dental tissue samples were(More)
The object of this study was to investigate whether laser-induced skin autofluorescence (LIF) and/or light reflectance spectra could provide a useful contrast between basal cell carcinoma (BCC) tissues and the surrounding healthy skin. Unstained human skin samples, excised from humans undergoing biopsy examination, were irradiated with a nitrogen laser(More)
In dermatology, the in vivo spectral fluorescence measurements of human skin can serve as a valuable supplement to standard non-invasive techniques for diagnosing various skin diseases. However, quantitative analysis of the fluorescence spectra is complicated by the fact that skin is a complex multi-layered and inhomogeneous organ, with varied optical(More)
Ablation of gelatin samples was performed by using a semiconductively preionized TEA CO2 laser, emitting pulses of the lower TEM mode, 100 ns duration, at a repetition rate of 2.4Hz. Ablation rate experiments were performed at a range of fluences from 2J cm−2 to 10J cm−2. Assuming that the absorption coefficient is much larger than the scattering(More)
A relatively new method for measuring optically induced forces on microparticles and cells, different from the conventional Brownian motion and viscous drag force calibration methods widely used, is introduced. It makes use of the phenomenon of dielectrophoresis for the calibration of optical tweezers through the dielectrophoretic force calculations. A pair(More)
Polytetrafluroethylene (PTFE) and other biocompatible polymers have been extensively used for sutures, vascular grafts and bone, and other hard tissue replacements. The use of surgical lasers for intervention on teflon-tissue interfaces has attracted a great deal of interest, as both the high intensity pulsed lasers and prosthetic biomaterials are in(More)
The aim of this work is the experimental and theoretical investigation of the influence of variable laser parameters (wavelength, fluence, pulse repetition rate) and of the optical and thermophysical properties of bone tissue (absorption coefficient, tissue inhomogeneity) as well as of the sample thickness on ablation thresholds and ablation rate. Ablation(More)