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Anticipation of pain is a complex state that may influence the perception of subsequent noxious stimuli. We used functional magnetic resonance imaging (fMRI) to study changes of activity of cortical nociceptive networks in healthy volunteers while they expected the somatosensory stimulation of one foot, which might be painful (subcutaneous injection of(More)
Although the spinal cord is the output station of the central motor system, little is known about the relationships between its functional activity and willed movement parameters in humans. We investigated here blood oxygenation level-dependent functional magnetic resonance imaging (fMRI) signal changes in the cervical spinal cord during a simple(More)
The present study explored the functional neuroanatomy of Foreign Accent Syndrome (FAS) in an Italian native speaker who developed an altered speech rhythm and melody following a circumscribed tumour to the left precentral gyrus. Structural, functional, fibre tracking and intraoperative findings were combined. No signs of dysarthria, apraxia of speech, or(More)
Perception of the final position of a moving object or creature is distorted forward along its actual or implied motion path, thus enabling anticipation of its forthcoming position. In a previous research, we demonstrated that viewing static snapshots that imply body actions activates the human motor system. What remains unknown, however, is whether(More)
The cortical system underlying perceptual ability to localize tactile and noxious cutaneous stimuli in humans is still incompletely understood. We used transcranial magnetic stimulation (TMS) to transiently interfere with the function of the parietal cortex, at different times after the beginning of noxious or non-noxious mechanical stimulation of the hairy(More)
At present, functional magnetic resonance imaging (fMRI) is one of the most useful methods of studying cognitive processes in the human brain in vivo, both for basic science and clinical goals. Although neuroscience studies often rely on group analysis, clinical applications must investigate single subjects (patients) only. Particularly for the latter,(More)
Expertise offers a unique insight into how our brain functions. The purpose of this experiment was to determine if motor system activity and functional connectivity between the cognitive system and sensorimotor system is differentially modulated by an individual's level of expertise. This goal was achieved through the acquisition of functional neuroimaging(More)
In this paper, we review blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) studies addressing the neural correlates of touch, thermosensation, pain and the mechanisms of their cognitive modulation in healthy human subjects. There is evidence that fMRI signal changes can be elicited in the parietal cortex by stimulation of(More)
Being able to estimate the fMRI-BOLD response following a single task or stimulus is certainly of value, since it allows to characterize its relationship to different aspects either of the stimulus, or of the subject's performance. In order to detect and characterize BOLD responses in single trials, we developed and validated a procedure based on an(More)
We describe involuntary language switching from L2 to L1 evoked by electro-stimulation in the superior temporal gyrus in a 30-year-old right-handed Serbian (L1) speaker who was also a late Italian learner (L2). The patient underwent awake brain surgery. Stimulation of other portions of the exposed cortex did not cause language switching as did not(More)