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An outbreak of viral encephalitis occurred in northern India in 2006. Attempts to identify an etiologic agent in cerebrospinal fluid by using reverse transcription-PCR showed positivity to enterovirus (EV) in 66 (21.6%) of 306 patients. Sequencing and phylogenetic analyses of PCR products from 59 (89.3%) of 66 specimens showed similarity with EV-89 and(More)
BACKGROUND Japanese encephalitis (JE) is a vaccine-preventable acute disease. We report the results of a phase 2/3 trial of JENVAC, a Vero cell-derived vaccine developed using an Indian strain of JE virus (JEV). METHODS JENVAC was administered in 2 doses 28 days apart, and immunogenicity was compared to that from a single dose of SA-14-14-2, the only(More)
Cryptography has been the core of security framework in Mobile Ad hoc Network (MANET). Cryptographic mechanisms mandate key management for a secure peer-to-peer communication. In MANET, due to limited energy and processing capabilities of mobile nodes, symmetric key management has been an active research area among others. Several research have been made in(More)
Location awareness among the participating nodes is one of the crucial requirements in designing of solutions for various issues related to Wireless Sensor Networks (WSNs). This paper discusses about a range free localization mechanism for WSN that operate in a three dimensional space. in this scheme, the sensor network is supposed to be comprised of mobile(More)
BACKGROUND An outbreak of acute encephalitis of unknown origin with high case fatality (183 of 329 cases) was reported in children from Andhra Pradesh state in southern India during 2003. We investigated the causative agent. METHODS Cell lines and peripheral blood lymphocyte co-cultures were used to isolate the causative agent from clinical samples.(More)
the epidemic PCR-ribotype 001. In particular, the identity between the 2 PCR ribotypes was 100% for the HMW proteins and 77% for the LMW proteins. This study provides convincing evidence that the S-layer is well conserved in C. diffi cile PCR-ribotype 027 strains and has high identity with the slpA of the epidemic PCR-ribo-type 001. Because C. diffi cile(More)
BACKGROUND & OBJECTIVES Japanese encephalitis virus (JEV) infection results in acute encephalitic illness. The affinity of JEV to different regions of brain and temporal changes in viral load have not been studied. This study was conducted to describe localization of JEV to different regions of the brain at different stages of disease in a rat model of(More)
Japanese encephalitis is an acute infection of the central nervous system caused by Japanese encephalitis virus (JEV). The importance of an effective humoral response in preventing JEV infection has already been established, although the contribution of cellular immunity remains unclear. This study used an experimental murine model to understand the(More)