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BACKGROUND An outbreak of acute encephalitis of unknown origin with high case fatality (183 of 329 cases) was reported in children from Andhra Pradesh state in southern India during 2003. We investigated the causative agent. METHODS Cell lines and peripheral blood lymphocyte co-cultures were used to isolate the causative agent from clinical samples.(More)
An outbreak of viral encephalitis occurred in northern India in 2006. Attempts to identify an etiologic agent in cerebrospinal fluid by using reverse transcription-PCR showed positivity to enterovirus (EV) in 66 (21.6%) of 306 patients. Sequencing and phylogenetic analyses of PCR products from 59 (89.3%) of 66 specimens showed similarity with EV-89 and(More)
During investigations into the outbreak of encephalitis in 1996 in the Kerala state in India, an arbovirus was isolated from a Culex tritaeniorhynchus mosquito pool. It was characterized as a Japanese encephalitis and West Nile virus cross-reactive arbovirus by complement fixation test. A plaque reduction-neutralization test was performed using hyperimmune(More)
Cryptography has been the core of security framework in Mobile Ad hoc Network (MANET). Cryptographic mechanisms mandate key management for a secure peer-to-peer communication. In MANET, due to limited energy and processing capabilities of mobile nodes, symmetric key management has been an active research area among others. Several research have been made in(More)
the epidemic PCR-ribotype 001. In particular, the identity between the 2 PCR ribotypes was 100% for the HMW proteins and 77% for the LMW proteins. This study provides convincing evidence that the S-layer is well conserved in C. diffi cile PCR-ribotype 027 strains and has high identity with the slpA of the epidemic PCR-ribo-type 001. Because C. diffi cile(More)
Scleroderma has been associated with exposure to many substances in the past ranging from vinyl chloride to silicon dioxide. In recent years there have been a number of case reports linking modern chemotherapy agents, such as the taxanes to the development of scleroderma like changes. We present a further case of scleroderma in association with chemotherapy(More)
Japanese encephalitis is an acute infection of the central nervous system caused by Japanese encephalitis virus (JEV). The importance of an effective humoral response in preventing JEV infection has already been established, although the contribution of cellular immunity remains unclear. This study used an experimental murine model to understand the(More)
BACKGROUND Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis, with ~50,000 cases reported annually worldwide. Vaccination is the only measure for prevention. Recombinant vaccines are an efficient and safe alternative for formalin inactivated or live attenuated vaccines. Nowadays, incorporation of molecular adjuvants has been the(More)
Location awareness among the participating nodes is one of the crucial requirements in designing of solutions for various issues related to Wireless Sensor Networks (WSNs). This paper discusses about a range free localization mechanism for WSN that operate in a three dimensional space. in this scheme, the sensor network is supposed to be comprised of mobile(More)
Theoretical methods to delineate antibody inducing epitopes have been employed to predict antigenic determinants on envelope glycoprotein (gpE) of Japanese encephalitis (JE), West Nile (WN) and Dengue (DEN) I-IV viruses. A predicted region on JE virus gpE 74CPTTGEAHNEKRAD87 was synthesized, conjugated to KLH (KLH-peptide) and used in immunization of mice. A(More)