M. Lengkong

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INTRODUCTION The efficacy of 5-HT(3)-receptor antagonists suggests a role of serotonin in the pathogenesis of postoperative nausea and vomiting (PONV). However, studies investigating the relationship between the turnover of serotonin and PONV were contradictory. Therefore we carried out a pilot study in order to find out whether results can be obtained that(More)
Objective:The mechanisms leading to the high incidence of postoperative vomiting (POV) after gynaecological laparoscopic surgery are still unknown. The effectiveness of POV-prophylaxis using H1 + H2-receptor antagonists has been demonstrated, suggesting a role for histamine in the pathogenesis of POV. However, histamine levels were not measured in these(More)
Die Wirksamkeit der 5-HT3-Rezeptorantagonisten zur Prophylaxe und Therapie von Übelkeit (Ü) und Erbrechen (E) nach Operationen in Allgemeinanästhesie legt eine Beteiligung des Serotonins in diesem Zusammenhang nahe. Allerdings sind die Ergebnisse der diesbezüglich durchgeführten Untersuchungen widersprüchlich. Mit dieser Pilotstudie soll untersucht werden,(More)
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