M Leirdal

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programmed cell death, is a process of active cellular self-destruction that plays a crucial role in cell development and homeostasis. In mammalian cells this process is regulated by a number of gene products. Among them, Bcl-2, Bcl-x L and Mcl-1 inhibit apoptosis, whereas others, such as Bax, Bak and Bad, activate apoptosis (Kroemer, 1997). Dysregulation(More)
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