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- Molly S. Bray, S. Prasad, +4 authors M L Hammarskjöld
- Proceedings of the National Academy of Sciences…
- 1994
Replication of human immunodeficiency virus type 1 (HIV-1) is dependent on the viral Rev protein. This protein acts in concert with the cis-acting rev-responsive element present in intron-containing… (More)
- Amy E Pasquinelli, Robert K Ernst, +5 authors J. E. Dahlberg
- The EMBO journal
- 1997
The constitutive transport elements (CTEs) of type D retroviruses are cis-acting elements that promote nuclear export of incompletely spliced mRNAs. Unlike the Rev response element (RRE) of human… (More)
- John H. Coyle, Brian W Guzik, +5 authors M L Hammarskjöld
- Molecular and cellular biology
- 2003
Cells normally restrict the nuclear export and expression of intron-containing mRNA. In many cell lines, this restriction can be overcome by inclusion of cis-acting elements, such as the Mason-Pfizer… (More)
- Earl J. Bergey, Misuk Cho, +4 authors M. J. Levine
- Journal of acquired immune deficiency syndromes
- 1994
Previous studies have suggested that salivary secretions may act as inhibitors of HIV-1 replication in vitro. This inhibitory activity was determined to be associated mainly with secretions obtained… (More)
- Jeffrey Y W Mak, M. Jiang, M. A. Wainberg, M L Hammarskjöld, David M. Rekosh, Laura B. Kleiman
- Journal of virology
- 1994
COS-7 cells transfected with human immunodeficiency virus type 1 (HIV-1) proviral DNA produce virus in which three tRNA species are most abundant in the viral tRNA population. These tRNAs have been… (More)
- A. J. Smith, Narasimhachar Srinivasakumar, M L Hammarskjöld, David M. Rekosh
- Journal of virology
- 1993
The roles of the human immunodeficiency virus precursor polyproteins Pr55gag and Pr160gag-pol in viral core assembly were studied in CMT3-COS cells. To do this, the precursors were expressed… (More)
- C Helga-Maria, M L Hammarskjöld, David M. Rekosh
- Journal of virology
- 1999
Although most reports defining the human immunodeficiency virus type 1 (HIV-1) genomic RNA packaging signal have focused on the region downstream of the major 5' splice site, others have suggested… (More)
- Ying Li, Yeou-cherng Bor, Yukiko Misawa, Yuming Xue, David Rekosh, M L Hammarskjöld
- Nature
- 2006
Alternative splicing is a key factor contributing to genetic diversity and evolution. Intron retention, one form of alternative splicing, is common in plants but rare in higher eukaryotes, because… (More)
- Yeou-cherng Bor, Jennifer L Swartz, Avril Morrison, David Rekosh, Michael R. Ladomery, M L Hammarskjöld
- Genes & development
- 2006
The Wilms' tumor 1 (WT1) gene plays an important role in mammalian urogenital development, and dysregulation of this gene is observed in many human cancers. Alternative splicing of WT1 RNA leads to… (More)
- Bartłomiej Guzik, Lyne Lévesque, +5 authors M L Hammarskjöld
- Molecular and cellular biology
- 2001
TAP, the human homologue of the yeast protein Mex67p, has been proposed to serve a role in mRNA export in mammalian cells. We have examined the ability of TAP to mediate export of Rev response… (More)