M. Jiménez-Fuentes

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In this work, we proposed a voltage-to-current cell based on a Complementary metal-oxide-semiconductor (CMOS) inverter designed by using floating gate transistors. We demonstrate its usefulness for the design of stair-type and sawtooth functions to be used in the implementation of a multiscroll chaotic oscillator. The main advantage of using floating gate(More)
The aim of our work here was to evaluate the immunogenicity of 60 mycobacterial antigens, some of which have not been previously assessed, notably a novel series of in vivo-expressed Mycobacterium tuberculosis (IVE-TB) antigens. We enrolled 505 subjects and separated them in individuals with and without latent tuberculosis infection (LTBI) vs. patients with(More)
BACKGROUND The aim of the study was to assess the correlation between the tuberculin skin test (TST) and in vitro interferon-gamma released assays (IGRAs) with risk factors for the spread of infection in smear positive pulmonary tuberculosis (TB) contacts. METHODS We recruited prospective contacts with smear positive pulmonary TB cases. We looked at human(More)
The design of a multiscroll chaotic oscillator based on the realization of a sawtooth function by using floating gate MOSFETs (FGMOS), is introduced. Basically, we propose the implementation of a FGMOS inverter to generate the nonlinear functions which are responsible of the equilibrium points of a continuous chaotic dynamical system, allowing the(More)
BACKGROUND To determine the prevalence of smoking and analyze associated factors in a cohort of patients diagnosed with tuberculosis (TB) in Spain between 2006 and 2013. METHODS Multicenter, cross-sectional, descriptive, observational study using a national database of TB patients, using logistic regression to calculate odds ratios (OR) and confidence(More)
RATIONALE The identification of patients with latent tuberculosis infection, who are at higher risk to develop active disease, is an important component of disease control. OBJECTIVES We aim to compare the usefulness of the QuantiFERON-TB Gold in-tube assay and the tuberculin skin test to predict the development of active tuberculosis during follow-up,(More)
BACKGROUND Smoking is a risk factor for tuberculosis (TB) infection and disease progression. Tobacco smoking increases susceptibility to TB in a variety of ways, one of which is due to a reduction of the IFN-γ response. Consequently, an impaired immune response could affect performance of IFN-γ Release Assays (IGRAs). OBJECTIVE In the present study, we(More)
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