M J Vermeulen

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BACKGROUND The incidence of necrotizing enterocolitis (NEC) and possibly also of sepsis is lower in preterm infants fed their own mother's milk (hereafter 'mother's milk') compared with formula-fed infants. It is unclear whether this is caused by the protective properties of breast milk or by the absence of cow's milk. Especially in early life, mother's(More)
Glutamine is a conditionally essential amino acid for very low-birth weight infants by virtue of its ability to play an important role in several key metabolic processes of immune cells and enterocytes. Although glutamine is known to be used to a great extent, the exact splanchnic metabolism in enterally fed preterm infants is unknown. We hypothesized that(More)
OBJECTIVES Very-low-birth-weight (VLBW) infants are dependent on parenteral nutrition after birth. A parenteral lipid emulsion with a multicomponent composition may improve growth and neurodevelopment and may prevent liver injury, which is often observed in association with long-term parenteral nutrition with pure soybean oil. Our aim was to evaluate the(More)
OBJECTIVE To test the hypothesis that an initial fraction of inspired oxygen (FiO2) of 30% during resuscitation of preterm infants results in less oxidative stress and is associated with improved clinical outcomes compared with an FiO2 of 65%. STUDY DESIGN Preterm infants of gestational age <32 weeks (n = 193) were randomized to start resuscitation with(More)
BACKGROUND Extremely preterm infants are at high risk of neonatal mortality and adverse outcome. Survival rates are slowly improving, but increased survival may come at the expense of more handicaps. METHODOLOGY/PRINCIPAL FINDINGS Prospective population-based cohort study of all infants born at 23 to 27 weeks of gestation in The Netherlands in 2007. 276(More)
Cat-scratch disease (CSD), caused by Bartonella henselae infection, can mimic malignancy and can manifest atypically. Reliable serological testing is therefore of great clinical importance. The diagnostic performance of immunofluorescence assay (IFA) and ELISA was evaluated in a group of Dutch patients with proven CSD (clinical diagnosis confirmed by PCR).(More)
Laboratory diagnosis of cat-scratch disease (CSD) mainly relies on serological testing for Bartonella henselae antibodies by indirect immunofluorescence (IFA) or enzyme-linked immunoassay (ELISA). In this study the current diagnostic value of seven B. henselae serological tests was evaluated, including both commercial and in-house IFA’s as well as in-house(More)
Recently, new guidelines for enteral feedings in premature infants were issued by the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition Committee on Nutrition. Nevertheless, practice proves difficult to attain suggested intakes at all times, and occurrence of significant potential cumulative nutritional deficits 'lies in wait' in the(More)
OBJECTIVE To assess the value of 1-h daytime awake oximetry as a means of weaning oxygen flows in infants with oxygen dependent chronic lung disease. METHODS A cohort study of oxygen dependent infants enrolled in a 3-month period. One hour of awake oximetry data were compared with equal time periods defined within a polysomnographic study and at the same(More)
PURPOSE Evaluation of ketogenic diet (KD) therapies for seizure control during pregnancy when safety and appropriate management become considerations. Until now, no information has been available on seizure reduction and human pregnancy related outcomes in women treated with KD therapies. METHOD We describe two cases of pregnant women with epilepsy(More)