Learn More
Conventional Fourier-transform infrared (FTIR) microspectroscopic systems are limited by an inevitable trade-off between spatial resolution, acquisition time, signal-to-noise ratio (SNR) and sample coverage. We present an FTIR imaging approach that substantially extends current capabilities by combining multiple synchrotron beams with wide-field detection.(More)
The critical questions into the cause of neural degeneration, in Alzheimer disease and other neurodegenerative disorders, are closely related to the question of why certain neurons survive. Answers require detailed understanding of biochemical changes in single cells. Fourier transform infrared microspectroscopy is an excellent tool for biomolecular imaging(More)
We report Fourier transform infrared spectro-microtomography, a nondestructive three-dimensional imaging approach that reveals the distribution of distinctive chemical compositions throughout an intact biological or materials sample. The method combines mid-infrared absorption contrast with computed tomographic data acquisition and reconstruction to enhance(More)
The new infrared chemical imaging beamline IRENI (Infrared Environmental Imaging) is the world's first multi-beam synchrotron-base IR imaging beamline. We extract 320(h)×25(v) mrad 2 from a dedicated bending magnet (BM 2) and split the fan of radiation into 12 individual IR beams that we rearrange into a 3×4 matrix to illuminate the sample homogeneously 1 ,(More)
  • F. Farazkhorasani, M. Isenor, +5 authors K. M. Gough
  • 2010
Fungi have pervasive and essential roles in plant survival that include symbiotic relationships wherein fungi trade services for food. While some species are plant pathogens that destroy crops and threaten food supplies, others participate in symbiotic relationships with plants, helping them acquire nutrients from soils. A better understanding of fungal(More)
The formation mechanism of the thermodynamically unstable calcite phase, very high Mg calcite, in biological organisms such as sea urchin or corallina algae has been an enigma for a very long time. In contrast to conventional methods such as KBr pellet Fourier Transform infrared (FTIR) spectroscopy and X-ray diffraction (XRD), FTIR microspectroscopy (FTIRM)(More)
New methods are needed to rapidly identify malaria parasites in blood smears. The coupling of a Focal Plane Array (FPA) infrared microscope system to a synchrotron light source at IRENI enables rapid molecular imaging at high spatial resolution. The technique, in combination with hyper-spectral processing, enables imaging and diagnosis of early stage(More)
  • 1