M I Gondra

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Nicotine administered in high doses intravenously (1 mg/kg) and intracochlearly (10 mM) exhibited very little effect on guinea pig cochlear potentials. When administered chronically (1-20 mg/kg, i.p. for 20 days), nicotine demonstrated no effect on cochlear potentials or the number of observed hair cell scars monitored 21 days after the treatment was(More)
Using tone burst stimuli with fixed parameters of rise time and duration, a functional relationship has been demonstrated between frequency and intensity of the stimulus and peak latency of electrocochleographic recordings. The feasibility of a "map" of the human cochlear partition has been shown for frequencies above 2 kHz.
A follow-up study of 35 children subjected to electrocochleography (Ecog) was conducted to determine (1) agreement of Ecog results with other audiometric measures obtained subsequently, and (2) accuracy of recommendations for patient management made on the basis of Ecog results. The latter was determined by parental experience, educational placement and(More)
Summary--Aminooxyacetic acid (AOAA; 1 MM) when perfused through the scala tympani of guinea pigs produced a biphasic reduction in the endocochlear potential, together with a shift in the input-output functions of the cochlear microphonics and the compound action potential of the cochlear nerve. Since the ionic (Na+, K+) content of the scala media was not(More)
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