M I Factor

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The role of the serotonin transporter protein (STP) in the development of somatoform [corrected] disorders was addressed in a correlational study of the levels of immunoreactive STP (IR-STP) using site-specific antibodies against the least conserved (among a group of other cotransporters) epitope at the C-terminal of STP and the level of anxiety symptoms in(More)
In a population of drug-free bipolar and unipolar depressed women, it was found that the concentration of serotonin sufficient to induce half-maximal shape change velocity in platelets is significantly (p less than 0.001) lower (0.13 +/- 0.0.04 microM) than that of closely matched controls (0.532 +/- 0.1 microM). This platelet concentration becomes higher(More)
The preparation of brain cells in the presence of diazepam leads to a 60-70% increase in benzodiazepine receptor density. Diazepam may promote the dissociation of endogenous inhibitors (modulators) and/or retard the dissociation of benzodiazepin receptors from the membrane to the medium. Routinely used procedures for tissue preparation reveal only part of(More)
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