M. I. Barannik

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The reaction of rat tissues was studied using the methods of light microscopy 4, 12, 18 days, 1, 2, 6 and 12 months after hypodermic implantation of polymeric films made of polyhydroxyalkanoates (PHA). It was found that polymer, like any foreign matter in an organism, become immediately covered by fibrin. By day 4, there the deformation and destruction of(More)
Morphological changes in tissues adjacent to the implant were studied 1, 2, 6, and 12 months after implantation of biodegradable suture materials (catgut thread, DemeTECH polyfilament thread, and Surgilactin monofilament thread) into subcutaneous fat of rats. Tissue reaction to implantation of different suture materials developed as usual in response to a(More)
Recent literature on the morphological results of the application of polymers produced from lactic acid (polylactides--PLA), contains a plethora of experimental and clinical data on the efficiency and safety of their use for the medico-biological purposes. However, the question on the actual rate of biological disintegration of PLA materials remains(More)
Tissue reactions, accompanying the degradation processes of polylactide (PLA) implants after their placement into the subcutaneous tissue, were studied by the methods of light microscopy in 6 month-old Wag rats (n=24) weighing 180-200 g. It was found that PLA implants became encapsulated by connective tissue. If the implant or its fragment had sharp margins(More)
Light microscopy was used to study connective tissue capsules formed around different silicone breast implants. It has been found that due to the activity of microfibroblasts to minimize the volume of foreign bodies, the capsule gradually shrinks; its inner surface deforms and develops an undulating appearance with a multitude of outgrowths or protrusions(More)
The method of light microscopy was used to study the reactions of the surrounding tissues to the implantation of non-degradable surgical materials (prolene 3/0 thread made from polypropelene, the composite grid made from polypropelene or polyester with polylactic acid) in the subcutaneous adipose tissue of rats 1, 2, 6 and 12 months after grafting. No less(More)
The processes developing in various rat tissues after implantation of polymeric polyhydroxyalkanoate (PHA) film fragments with adsorbed autologous multipotent stromal (mesenchymal) cells of bone marrow origin (AMMSCBM), were studied by methods of light microscopy. After the implantation of PHA film with AMMSCBM, the number of blood vessels in the(More)
The reaction of various tissues of rats to implantation of polyhydroxyalkanoate films and ultrafine fibers was studied by optic microscopy. Implantation of polyhydroxyalkanoate films into the abdominal cavity caused a peritoneal reaction, leading after 1 month to the formation of fibrous adhesions between polyhydroxyalkanoate and intestinal loops. Under the(More)
The objective of this study was to examine the peculiarities of tissue reactions during the degradation of "Collost" bioplastic material on the collagen basis with completely preserved fibrous structure, after its implantation into the bone tissue defect. The defect in bone tissue sized 1-2 mm x 3-5 mm was created in tibial condyle. The study was performed(More)