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Conduction in demyelinated and remyelinating axons has been simulated with a computational model. The calculations made use of recent determinations of ionic channel densities in the internodal… Continue Reading
The current state of software engineering practices in medical software development is discussed. The authors focus on patient safety (freedom from harm by a medical device) and patient vulnerability… Continue Reading
A computer program has been developed for simulation of electrical activity in neurons with complex branching morphology, multiple channel types, and inhomogeneous channel distribution. The program… Continue Reading
Three simple improvements are presented which, for a given accuracy, result in a 10-20-fold decrease in computation time for simulation of arbitrarily branched active cables with Hodgkin Huxley (HH)… Continue Reading