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The GIS software sector has developed rapidly over the last ten years. Open Source GIS applications are gaining relevant market shares in academia, business, and public administration. In this paper, we illustrate the history and features of a key Open Source GIS, the Geographical Resources Analysis Support System (GRASS). GRASS has been under development(More)
OBJECTIVE To evaluate whether Constraint-Induced Movement therapy (CI therapy) may benefit chronic upper extremity hemiparesis in progressive multiple sclerosis (MS). METHODS Five patients with progressive MS, who had chronic upper extremity hemiparesis and evidence for learned non-use of the paretic limb in the life situation, underwent 30 hours of(More)
Chorea-acanthocytosis (CHA) is a rare inherited neurologic disorder with peripheral red cell acanthocytes and normal serum lipoprotein levels. To date, 8 families with the disorder have been reported outside of Japan. We describe 4 patients in 3 families with CHA and review the clinical presentations in previous reports. In addition, we report magnetic(More)
OBJECTIVE To determine whether the combination of Constraint-Induced Movement Therapy (CIMT) and conventional rehabilitation techniques can produce meaningful motor improvement in chronic stroke patients with initially fisted hands. DESIGN Case series. SETTING University hospital outpatient laboratory. PARTICIPANTS Consecutive sample (N=6) >1 year(More)
BACKGROUND AND PURPOSE Constraint-induced movement therapy is a set of treatments for rehabilitating motor function after central nervous system damage. We assessed the roles of its 2 main components. METHODS A 2 × 2 factorial components analysis with random assignment was conducted. The 2 factors were type of training and presence/absence of a set of(More)
PURPOSE The initial version of Constraint-Induced Aphasia Therapy (CIAT I) consisted of a single exercise. This study sought to evaluate the feasibility for future trials of an expanded and restructured protocol designed to increase the efficacy of CIAT I. METHOD The subjects were 4 native English speakers with chronic stroke who exhibited characteristics(More)
OBJECTIVE To evaluate in a preliminary manner the feasibility, safety, and efficacy of Constraint-Induced Movement therapy (CIMT) of persons with impaired lower extremity use from multiple sclerosis (MS). DESIGN Clinical trial with periodic follow-up for up to 4 years. SETTING University-based rehabilitation research laboratory. PARTICIPANTS A(More)