M H de Groodt-Lasseel

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The morphological classification of the different neuronal cell types is generally accepted and expanded by us; nevertheless, immunohistochemically and electrophysiologically the existence of clear-cut categories of enteric neurons is frequently questioned. The immunohistochemical results demonstrated in this study, however, provide the first direct link(More)
The presence and topographical distribution of nitrergic neurons in the enteric nervous system (ENS) of the pig small intestine have been investigated by means of nitric oxide synthase (NOS) immunocytochemistry and nicotinamide dinucleotide phosphate diaphorase (NADPHd) histochemistry. Both techniques yielded similar results, thus confirming that within the(More)
BACKGROUND Birds have a limited number of resident macrophages in the normal steady-state respiratory tract. The discovery of phagocytes in lavages of lung from birds contrasts with findings that phagocytes are seldom seen in investigations in situ. An electron microscopic study was performed in the respiratory units, the parabronchi, and air capillaries in(More)
This short review reports the latest insights into the structural organization of the enteric nervous system, with special emphasis on the intrinsic innervation of the intestinal tract of large omnivorous mammals such as the pig. Using various techniques, including lesion experiments, morphological and neurochemical features of distinct neuronal populations(More)
Calcitonin gene-related peptide (CGRP)-containing perikarya and axonal processes were localized by preembedding electron-microscopic immunocytochemistry in the porcine small intestine. Immunoreactive well-defined type II neurons were localized in the plexus myentericus, and plexus submucosus externus and internus. In some cases, they were found in direct(More)
The occurrence and distribution of the vitamin-D-induced calcium-binding protein, calbindin-D28K, has been studied in the brain of a cartilaginous fish using immunohistochemical techniques. A strong immunoreactivity was found in the perikarya, dendrites and axons of neurons located in the nucleus interstitialis commissurae anterioris, the nucleus medialis(More)
The occurrence and distribution of neuroepithelial endocrine (NEE) cells was demonstrated electron- and fluorescence-microscopically in the lungfish Protopterus aethiopicus. They were only found to occur solitarily in the basal part of the cilio-mucous epithelium which is restricted to the pneumatic duct and adjacent parts of the common anterior chamber.(More)
Avian air capillaries are delicate structures compared to the mammalian pulmonary alveolus. A transmission and scanning electron microscopic study was carried out on several species of birds with the aim of determining the support structures of the avian gas-exchange mantle. Lung tissue of two bird species belonging to strong flying birds (pigeon and barn(More)
Calcitonin-gene-related-peptide (CGRP)-like immunoreactivity was localized in nerve fibres, neuronal somata and in mucosal endocrine cells of the human small intestine. Immunoreactive enteric neurons were more numerous in the submucous plexuses than in the myenteric plexus. Morphologically, they predominantly had the appearance of type II neurons. The(More)
Despite extensive knowledge of the neuroepithelial endocrine (NEE) system in the lungs of species of various vertebrate classes, data on avians are limited. The present investigation deals with the light- and electron-microscopical immunocytochemistry and morphology of pulmonary NEE cells in the quail, Coturnix coturnix. Light-microscopically, serotonin(More)