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  • David L. Nelson, Susan A. Ledbetter, +5 authors Charles Thomas Caskey
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1989 (First Published: 1 September 1989)
  • Current efforts to map the human genome are focused on individual chromosomes or smaller regions and frequently rely on the use of somatic cell hybrids. We report the application of the polymeraseContinue Reading
  • David L. Nelson, Andrea Ballabio, +7 authors Charles Thomas Caskey
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1991 (First Published: 15 July 1991)
  • Over 400 yeast artificial chromosome (YAC) clones were isolated from the human X chromosome, and 110 of these were assigned to regions defined by chromosome translocation and deletion breakpoints.Continue Reading