M F Rouleau

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For more than a week prior to the emergence of a hind limb, a steady electric current is driven out of the ventrolateral flank in the immature axolotl, returning through the integument in adjacent regions of the body. A marked peak in the density of this outcurrent could be observed over the exact area of hind limb formation 4 to 6 days prior to its(More)
A radioautographic method was used to locate specific binding sites for biologically active iodinated calcitonin in rats. The results show that the subfornical organ of the brain, a suspected water regulating organ, is a specific target for calcitonin. The hormone predominantly binds to processes of tanycytes, suggesting that these ependymal cells play an(More)
We have compared the anatomy of immature axolotl integument from limb-forming regions with adjacent non-limb-forming regions of the flank, concentrating on the earliest stages of limb bud development. We have extended these observations to include prominent buds just prior to their differentiation. At the ultrastructural level, we note striking differences(More)
An in vivo binding assay using radioautography was employed to visualize calcitonin receptors in rat tissues. At 2 min after intravenous injection of biologically active 125I-salmon calcitonin, free hormone was separated from bound hormone by intracardiac perfusion with lactated Ringer's followed by fixation with 2.5% glutaraldehyde. Various tissues were(More)
The orbicularis oculi branch of the facial nerve was transected in two groups of 15 cats. Following section of the nerve, a specimen was removed for histological studies; then, using microscopic techniques the epineurium was sutured (nylon 10:0) in the first group, and the perineurium in the second. They were then followed for 100 days. Results rely on(More)
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