M Erwin S H Tan

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BACKGROUND The impact of meteorological conditions on the occurrence of various cardiovascular events has been reported internationally. Data about the Dutch situation are limited. OBJECTIVES We sought to find out a correlation between weather conditions and the incidence of major acute cardiovascular events such as type A acute aortic dissection (AAD),(More)
BACKGROUND AND AIM OF THE STUDY Concerns have been recently raised regarding the postoperative decrease in platelet count after aortic valve replacement (AVR). Thus, a retrospective analysis was conducted of patients after AVR with regards to postoperative platelet count. METHODS The data were analyzed from all patients undergoing AVR with (n = 829) or(More)
BACKGROUND We report our experience with surgery for acute type A aortic dissection with involvement of the aortic arch. METHODS From January 1986 to December 2001, 277 patients underwent surgery for acute type A aortic dissection. In 70 patients (25.3%), surgery was extended into the aortic arch: hemiarch and total arch replacement in 53 (75.7%) and 17(More)
Laboratory and clinical data have implicated endotoxin as an important factor in the inflammatory response to cardiopulmonary bypass. Alkaline phosphatase prevents endotoxin-induced systemic inflammation in animals and humans. We assessed the effects of the administration of bovine intestinal alkaline phosphatase on surgical complications in patients(More)
A 75-year-old man underwent a Bentall procedure and hemi-arch replacement with a Biovalsalva conduit (Vascutek Terumo, Renfrewshire, Scotland) and concomitant coronary re-vascularisation. Three days later, the patient underwent an uneventful re-sternotomy due to cardiac tamponade. During the procedure, blood was drained to release the tamponade; however, no(More)
BACKGROUND The European system for cardiac operative risk evaluation, the most popular European scoring system in cardiac surgery, uses the extracardiac arteriopathy as a risk factor for early mortality. We studied the effect of peripheral vascular disease (PVD) on early and late mortality in a large group of patients undergoing isolated coronary artery(More)
OBJECTIVE To elucidate the mechanisms of Brahma-related gene 1 (Brg1) involvement in the pathophysiologic processes of aortic dissection. METHODS Seventeen dissecting, 4 dilated, and 10 healthy human aorta samples were collected. Expression of Brg1 in the medium of aorta was evaluated by quantitative real-time polymerase chain reaction, Western blot, and(More)
OBJECTIVES The aim of this study was to investigate the mid-term haemodynamic and clinical results after aortic valve replacement (AVR) using the Sorin Freedom Solo (SFS) stentless bioprosthesis, compared with the standard Carpentier Edwards Perimount (CEP) stented bioprosthesis. METHODS In this retrospective cohort study of prospectively collected data,(More)
Concomitant lung malignancy and coronary artery disease is uncommon. When the left lung is involved, the approach is considered to be staged or through left thoracotomy. We present a patient who was operated on for left pneumonectomy and off-pump coronary surgery through a midline sternotomy with the use of a Medtronic Starfish 2 Heart Positioner.