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A randomized trial of combined modality therapy employing combination chemotherapy (cyclophosphamide (CTX) and methotrexate (MTX), CTX, MTX and Vincristine (VCR) and CTX, VCR and high-dose MTX with citrovorum rescue) and radiation therapy was compared to cyclophosphamide and radiation therapy in 258 patients with pulmonary small cell carcinoma. Patients(More)
We studied the thyroid function of 64 patients with Hodgkin's disease who received mantle irradiation during the period 1966 to 1976. More than two thirds (44 of 64) had some thyroid dysfunction. Twenty had mild dysfunction manifested by an abnormal thyroid-stimulating hormone response to thyrotropin-releasing hormone. Twenty had what could be termed(More)
Nine patients with multiple myeloma were treated with whole bone marrow irradiation. Six had heavily pretreated disease refractory to chemotherapy. Three had stable disease lightly pretreated by chemotherapy. A modification of the "three and two" total nodal radiation technique was employed. Although varying and often severe treatment related cytopenia(More)
  • M E Tulloh
  • Canadian journal of surgery. Journal canadien de…
  • 1981
Carcinoma of the pancreas, presenting so often at an inoperable stage, has been the subject of many nonoperative therapeutic regimens. Radiotherapy using high-dose techniques has been shown to produce 45% palliation. The author discusses in detail radical techniques, with and without chemotherapy, that have resulted in a modest improvement in survival. But(More)
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