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OBJECTIVES Our aim was to design and evaluate a new and easily administered recombinant tissue-type plasminogen activator (rt-PA) regimen for thrombolysis in acute myocardial infarction (AMI) based on established pharmacokinetic data that improve the reperfusion success rate. BACKGROUND Rapid restoration of Thrombolysis in Myocardial Infarction (TIMI)(More)
Today, profound insight into the clotting and fibrinolytic systems during therapeutic thrombolysis is offered by a variety of laboratory assays. While the purpose of scientific investigations is to increase the knowledge on changes imposed by the mechanism of thrombolysis, the rationale for performing coagulation assays during thrombolytic therapy is to(More)
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