M. E. S. Mendes

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First submission on 23/10/12; last submission on 12/12/12; accepted for publication on 19/12/12; published on 20/06/13 1. Clinical Pathologist by Faculdade de Medicina da Universidade de São Paulo (FMUSP); chief at the Technical Section of Blood Biochemistry from the Central Laboratory Division of FMUSP Clinical Hospital/Laboratory of Medical Investigation(More)
New cyclosporine A (CsA) formulations must prove their bioequivalence to Neoral, the reference CsA formulation, to allow free prescription for the patients. The aim of this study was to compare the pharmacokinetics (PK) of a new CsA formulation (Zinograf-ME), produced by Strides-Arcolab, to Neoral and to demonstrate their interchangeability in stable renal(More)
This paper discusses how a variable pedagogical model can be supported in a network based teaching and learning environment. This work is being developed as part of the EU/IST project, CANDLE (Collaborative and Network-based Distributed Learning Environment), developing re-usable network based learning material. Online material for learning takes several(More)
Abstract: In this paper we present an approach to organize Web-accessible courseware according to knowledge domains, by means of fuzzy clustering. A new modified version of the Fuzzy C-Means clustering algorithm that employs a non-Euclidean metric is proposed and some preliminary trials with the new metric are presented. The experimental results show that(More)
Tradescantia pallida cv. purpurea, a plant species widely employed for ornamentation in Brazil, has been successfully used for monitoring the genotoxicity of various agents by the micronucleus assay. To amplify knowledge about its suitability as a bioindicator species, its capacity for accumulating trace elements from urban air pollution was evaluated. T.(More)
The work described in this paper has been carried out in the context of a network-based teaching and learning system. In such systems, the need to find relevant learning resources to a particular knowledge domain arises. This need comes not only from a learning perspective, but also from an authoring perspective. From the authoring point of view, the re-use(More)
Introduction: The results of blood gas analysis using different instrumentation can vary widely due to the methodological differences, the calibration procedures and the use of different configurations for each type of instrument. Objective: The objective of this study was to evaluate multiple analytical systems for measurement of blood gases, electrolytes(More)
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