M. E. Mazurov

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The problem of the control of cardiac rhythm has been considered in terms of the general theory of the synchronization of relaxation systems. The main pathways of the control of cardiac rhythm have been determined: (1) control with regard for the features of synchronization of relaxation systems during the formation of the unified heart rhythm due to the(More)
Dynamic processes during the establishment of the uniform heart rhythm have been considered. It was shown that, during the establishment of the uniform rhythm as a result of mutual synchronization, the establishment of phase parities and a delay of excitation occur. The establishment of the uniform rhythm in a system of cooperating pacemakers of relaxation(More)
The most significant experimental data about the formation of a uniform rhythm of the sinoatrial unit of the heart for both the intact sinoatrial unit of the heart and cardiomyocytes in cellular structures are presented. The basic mathematical models for studying the processes of synchronization in the sinoatrial unit of the heart are described, including(More)
22 In addition to electrical connections between cells, the sinus node of the hart has been found to have mechanical–electrical connection with atria, which are relatively heavy and have a considerable effect on the sinus node. Electrophysiological studies have demonstrated that the excitation of atria in an ectopic high-frequency rhythm changes the sinus(More)
The excitation of the sinoatrial unit from heart auricles of the frog has been studied. Potentials were recorded by means of microelectrodes inserted to pacemaker of the sinoatrial unit. It has been established that auricles can impart the rhythm to the sinoatrial unit due to electric and electromechanical influence, and electromechanical influence is of(More)
AIM to compare clinical results of linear ablation vs. PVI approach in patients with paroxysmal AF and to estimate theoretical probability of 4-waves re-entry to eliminate as a results of the both ablative techniques formatting by means left atrial geometry two-dimensional mathematical modeling. MATERIAL AND METHODS Clinical phase. Study was conducted on(More)
Principal physiological hypotheses concerning the setting of united rhythm in the heart sinoatrial node (SAN) are considered. A mathematical model of SAN is proposed which takes into account properties of individual elementary pacemakers and their interaction. Assuming paired interaction of the pacemakers there are revealed the main P.D. parameters,(More)
AIM 1) to create Perimitral Atrial Flutter (PMAFL) model and estimate theoretical probability of elimination of perimital reetntry using left atrial geometry two-dimensional mathematical modeling and ablative formatting; 2) to compare clinical results of PMAFL ablation by means of mitral vs inferioseptal isthmus ablation and mathematical modeling data. (More)