M E Janszen

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Using a phycoerythrin-conjugated antibody to the p55 chain of the interleukin 2 receptor, normal blood lymphocytes were found to be on average 30% positive for this marker. Two-thirds of these cells are in the CD4 subset and most are within the CD45RA negative fraction associated with activated or memory T cells.
Two novel T cell specific activation antigens were characterized and were defined by monoclonal antibodies developed against mitogen-stimulated human T cells. These antigens, designated as L-35 and L-36 were expressed on both the CD 4(Leu-3) and the CD 8(Leu-2) subsets of activated but not resting T cells. Moreover these antigens were not expressed on a(More)
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