M. E. Diatroptov

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We carried out a prolonged investigation of thymic cells, melatonin and corticosterone biorhythms in male Wistar rats. The total number ofthymic cells, lymphocyte numbers in the peripheral blood and percentrage of CD3+ lymphocyte had a 6-days period of fluctuation. The other period of fluctuation in 4 days was found in the dynamics width of subcapsular(More)
The dynamics of serum testosterone was studied in laboratory male rats kept separately from females. Infradian rhythm of changes in testosterone level equal to 4 days and ultradian (within 24 h) periods equal to 160 and 480 min were detected. The maximum serum level of testosterone in male rats was synchronized with the greatest number of estrous females.
Infradian rhythms of esophageal epithelium mitotic activity were studied in male Wistar rats of two age groups: 35-45 days (prepubertal) and 3-4 months (adults). Studies of the time course of esophageal epithelium mitotic indexes in adult males showed 4- and 12-day biorhythms, while prepubertal rats exhibited only 4-day infradian biorhythms of this(More)
Many-day rhythms of proliferative activity of the corneal and esophageal epithelium and serum corticosterone levels were studied in adult male Wistar rats. We detected a 4-day rhythm of proliferative activity of esophageal epithelium negatively correlating with corticosterone level. A more pronounced decrease in the number of mitoses in the esophageal and(More)
In the course of 15 days, the thyroxine and corticosterone level was measured daily in blood serum of molting starlings, Sturnus vulgaris, by use of enzyme immunodetection method. Revealed are three-day rhythm in changes of thyroxine level and four-day one in changes of corticosterone level, both rhythms being synchronized in different birds. A beginning of(More)
Inbred animals serve as an adequate model to study the role of genetic factors in adaptive, disadaptive, and pathological processes. Morphofunctional study of the immune system was performed on intact BALB/c and C57Bl/6 mice. The structural and functional parameters of the immune system in BALB/c and C57Bl/6 mice differ under physiological conditions. In(More)
The level of cytokines produced by ConA activated splenocytes was studied in male BALB/c and C57Bl/6 mice after single and repeated cold exposure (−20°C, 3 min). Single cold exposure significantly decreased IL-2, -3, -4, -5, -10, -12, IFN-γ production in BALB/c mice and decreased IL-2 content and increased TNF-α level in C57Bl/6 mice. Repeated cold exposure(More)
The relationship between the phase of 4-day serum corticosteroid biorhythm and resistance to acute hypobaric hypoxia was studied in male rats. Single evaluations of hypoxic resistance of Wistar rats during the same time of the day have shown that the lifespan of animals is significantly longer during the 4-day biorhythm acrophase than during the bathyphase.(More)
Everyday dynamics of corticosterone and thyroxin levels on blood serum, as well as esophageal epithelium proliferation activity in Japanese quail males, have been investigated over a period of 16 days. It was estimated that different individuals synchronically exhibited a 4-day rhythm of the corticosterone serum level. The thyroxin level displayed a 3-day(More)
We studied the effect of pinealectomy on the parameters of 4-day infradian biorhythms in mature male Wistar rats. It was shown that pinealectomy did not change the period and phase of infradian biorhythm of total locomotor activity, serum concentrations corticosterone and testosterone, and mitotic index of esophageal epithelium. No significant changes in(More)