M. E. Diatroptov

Learn More
In the course of 15 days, the thyroxine and corticosterone level was measured daily in blood serum of molting starlings, Sturnus vulgaris, by use of enzyme immunodetection method. Revealed are three-day rhythm in changes of thyroxine level and four-day one in changes of corticosterone level, both rhythms being synchronized in different birds. A beginning of(More)
Many-day rhythms of proliferative activity of the corneal and esophageal epithelium and serum corticosterone levels were studied in adult male Wistar rats. We detected a 4-day rhythm of proliferative activity of esophageal epithelium negatively correlating with corticosterone level. A more pronounced decrease in the number of mitoses in the esophageal and(More)
Inbred animals serve as an adequate model to study the role of genetic factors in adaptive, disadaptive, and pathological processes. Morphofunctional study of the immune system was performed on intact BALB/c and C57Bl/6 mice. The structural and functional parameters of the immune system in BALB/c and C57Bl/6 mice differ under physiological conditions. In(More)
The dynamics of serum testosterone was studied in laboratory male rats kept separately from females. Infradian rhythm of changes in testosterone level equal to 4 days and ultradian (within 24 h) periods equal to 160 and 480 min were detected. The maximum serum level of testosterone in male rats was synchronized with the greatest number of estrous females.
The level of cytokines produced by ConA activated splenocytes was studied in male BALB/c and C57Bl/6 mice after single and repeated cold exposure (-20 degrees C, 3 min). Single cold exposure significantly decreased IL-2, -3, -4, -5, -10, -12, IFN-gamma production in BALB/c mice and decreased IL-2 content and increased TNF-alpha level in C57Bl/6 mice.(More)
The blood serum thyroxine and corticosterone levels of molting starlings (Sturnus vulgaris) were determined daily by enzyme immunoassay over 15 days. A 3-day rhythm for changes in the thyroxine content and a 4-day rhythm for corticosterone were observed, taking place synchronously in different individuals. The beginning of new flight feather growth(More)
Chronic endotoxicosis was modeled by subcutaneous injection of the sepharose in complex with LPS. In these conditions we have studied morphofunctional changes of the immune system of BALB/c and C57Bl/6 mice, which are characterized by the different types of the immune response (Th2 type is predominant in BALB/c, Th1--in C57Bl/6). In the 1st-7th day t in the(More)
We studied the effect of pinealectomy on the parameters of 4-day infradian biorhythms in mature male Wistar rats. It was shown that pinealectomy did not change the period and phase of infradian biorhythm of total locomotor activity, serum concentrations corticosterone and testosterone, and mitotic index of esophageal epithelium. No significant changes in(More)
We carried out a prolonged investigation of thymic cells, melatonin and corticosterone biorhythms in male Wistar rats. The total number ofthymic cells, lymphocyte numbers in the peripheral blood and percentrage of CD3+ lymphocyte had a 6-days period of fluctuation. The other period of fluctuation in 4 days was found in the dynamics width of subcapsular(More)
Everyday dynamics of corticosterone and thyroxin levels on blood serum, as well as esophageal epithelium proliferation activity in Japanese quail males, have been investigated over a period of 16 days. It was estimated that different individuals synchronically exhibited a 4-day rhythm of the corticosterone serum level. The thyroxin level displayed a 3-day(More)