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With the growing focus on supply chain management, firms realize that inventories across the entire supply chain can be more efficiently managed through greater cooperation and better coordination. This paper presents a comprehensive and up-to-date review of the joint economic lot sizing problem (JELP) and also provides some extensions of this important(More)
OBJECTIVE To estimate the cost to the health system of obstetric complications due to female genital mutilation (FGM) in six African countries. METHODS A multistate model depicted six cohorts of 100,000 15-year-old girls who survived until the age of 45 years. Cohort members were modelled to have various degrees of FGM, to undergo childbirth according to(More)
A screening questionnaire is an important tool for early diagnosis of neurological disorders, and for epidemiological research. This screening instrument must be both feasible and valid. It must be accepted by the community and must be sensitive enough. So, the aim of this study was to prepare different Arabic screening questionnaires for screening(More)
In this study, we attempt to target both the urokinase plasminogen activator and the mitogen-activated protein kinase pathway in acute myeloid leukemia (AML) cell lines and primary AML blasts using PrAgU2/LF, a urokinase-activated anthrax lethal toxin. PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be(More)
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