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Embryonic stem cells (ESCs) represent a promising tool for cell therapy, regenerative medicine and tissue repair. At the same time they constitute an invaluable model for basic investigations in developmental biology, nuclear reprogramming and differentiation process. ESCs are very unique due to their unlimited self-renewal ability and high plasticity that(More)
Embryonic stem cells (ESCs) hold great promise for therapeutic use and represent a unique tool for investigating the process of self-renewal and differentiation. The properties that make ESCs unique are their capacity of unlimited self-renewal coupled with the property of re-entering the developmental process if returned inside a blastocyst. Such plasticity(More)
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