M. Cohn

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There are three questions under re-examination here that have been inspired by Bretscher's 'Two-step, Two-signal' model. First, what is the nature of the steps required in order for antigen-responsive cells to become effectors? Second, how does the immune system get started? Third and the most troublesome, what is the mechanism that relates the delivery of(More)
As many teachers know, Randall Jarrell's The Bat-Poet is not only a touching , sensitively rendered fairy tale. It is also a very effective—and commonly employed—introduction to both the reading and writing of poetry. Besides suggesting Jarrell's complex and dialectical theory of poetry, 1 The Bat-Poet also touches on the competing impulses that might drive(More)
In analysing the Zinkernagel and Hengartner's 'Credo 2004,' Anderson introduces his 'development-context model' for the immunity-tolerance discrimination. He compares this model with the 'geographical model of Credo 2004' and our 'time-based two-signal model'. The discussion here deals with the advantages and limitations of the Anderson model considered(More)
In this paper, we describe an ongoing collaborative research project between the Universities of California at Berkeley and San Francisco with Endorobotics Corporation to develop milli-robotic tools for remote, minimally invasive surgery. We describe the limitations of current surgical practice and then describe the technological and scientific issues(More)
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